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Showing 1 to 12 of 1747 entries
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The race toward equity: increasing racial diversity in cancer research and cancer care

pipeline programs

Weeraratna AT.
GSID: 1D6-A1PpFU0J
DC Brady, AT Weeraratna - Cancer discovery, 2020 - AACR

The Race toward Equity: Increasing Racial Diversity in Cancer Research and Cancer Care Page 1 VIEWS OctOber 2020 CANCER DISCOVERY | OF1 Science in Society The Race …

Serum peptidome profiling for the diagnosis of colorectal cancer: discovery and validation in two independent cohorts.

Oncotarget

Wang H, Luo C, Zhu S, Fang H, Gao Q, Ge S, Qu H, Ma Q, Ren H, Wang Y, Wang W.
PMID: 28938643
Oncotarget. 2017 Jul 26;8(35):59376-59386. doi: 10.18632/oncotarget.19587. eCollection 2017 Aug 29.

Colorectal cancer (CRC) is one of the most common malignant neoplasms worldwide. Except for the existing fecal occult blood test, colonoscopy and sigmoidoscopy, no widely accepted

CD4.

Cancer discovery

[No authors listed]
PMID: 28450427
Cancer Discov. 2017 Jun;7(6):OF3. doi: 10.1158/2159-8290.CD-NB2017-063. Epub 2017 Apr 27.

Temporary removal of CD4

Nivolumab Approved for Liver Cancer.

Cancer discovery

[No authors listed]
PMID: 28978557
Cancer Discov. 2017 Nov;7(11):OF3. doi: 10.1158/2159-8290.CD-NB2017-138. Epub 2017 Oct 04.

The FDA granted accelerated approval to nivolumab for second-line treatment of advanced hepatocellular carcinoma, making it just the third drug on the market for the disease. The PD-1 inhibitor is approved for patients who cannot tolerate sorafenib and those...

Targeting Angiogenesis in Bladder Cancer.

Cancer discovery

[No authors listed]
PMID: 28978558
Cancer Discov. 2017 Nov;7(11):OF2. doi: 10.1158/2159-8290.CD-NB2017-140. Epub 2017 Oct 04.

Findings from the phase III RANGE study indicate that adding ramucirumab to docetaxel may improve progression-free survival for patients with advanced or metastatic urothelial carcinoma whose disease is refractory to platinum chemotherapy.

FDA OKs Abemaciclib for ER+, HER2- Breast Cancer.

Cancer discovery

[No authors listed]
PMID: 28978559
Cancer Discov. 2017 Nov;7(11):OF1. doi: 10.1158/2159-8290.CD-NB2017-141. Epub 2017 Oct 04.

The FDA has approved abemaciclib for women with advanced or metastatic ER-positive, HER2-negative breast cancer whose disease has progressed on endocrine therapy. This is the third CDK4/6 inhibitor to get the agency's go-ahead in 2.5 years.

Profiling Response, Resistance to Immunotherapy.

Cancer discovery

[No authors listed]
PMID: 28356263
Cancer Discov. 2017 May;7(5):OF2. doi: 10.1158/2159-8290.CD-NB2017-045. Epub 2017 Mar 29.

In a longitudinal analysis of patients with metastatic melanoma who received sequential therapies targeting CTLA-4, then PD-1 upon disease progression, researchers have discovered that high copy-number loss in recurrent regions of the tumor genome is associated with resistance to...

FDA Approves Second CAR T-cell Therapy.

Cancer discovery

[No authors listed]
PMID: 29113977
Cancer Discov. 2018 Jan;8(1):5-6. doi: 10.1158/2159-8290.CD-NB2017-155. Epub 2017 Nov 07.

The FDA approved the chimeric antigen receptor T-cell therapy axicabtagene ciloleucel, making it the second such treatment for blood cancers in the United States. The therapy is indicated for adults with certain non-Hodgkin lymphomas who have tried at least...

Start-ups Bring AI to Pathology.

Cancer discovery

[No authors listed]
PMID: 29475882
Cancer Discov. 2018 Apr;8(4):376. doi: 10.1158/2159-8290.CD-NB2018-019. Epub 2018 Feb 23.

New startups are developing pattern-recognition algorithms that could one day help pathologists more accurately spot tumors on digitized tissue images, thereby aiding in diagnosis, treatment, drug discovery, and more.

MEK Binding to KSR Promotes Allosteric Activation of BRAF.

Cancer discovery

[No authors listed]
PMID: 29475885
Cancer Discov. 2018 Apr;8(4):385. doi: 10.1158/2159-8290.CD-RW2018-033. Epub 2018 Feb 23.

KSR-MEK complexes allosterically activate BRAF, which then phosphorylates a second MEK molecule.

Crowdsourcing to Curb Bad Science.

Cancer discovery

[No authors listed]
PMID: 26272490
Cancer Discov. 2015 Oct;5(10):1008. doi: 10.1158/2159-8290.CD-NB2015-118. Epub 2015 Aug 13.

No abstract available.

$100M Africa Initiative Targets Childhood Cancer.

Cancer discovery

[No authors listed]
PMID: 28331005
Cancer Discov. 2017 May;7(5):447-448. doi: 10.1158/2159-8290.CD-NB2017-038. Epub 2017 Mar 22.

The Bristol-Myers Squibb Foundation have teamed up with Texas Children's Cancer and Hematology Centers and Baylor College of Medicine on a $100 million initiative to improve pediatric cancer care in sub-Saharan Africa. Organizers are partnering with local governments to...

Showing 1 to 12 of 1747 entries